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Publication Detail
Joint reconstruction of PET-MRI by exploiting structural similarity
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Publication Type:Journal article
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Publication Sub Type:Article
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Authors:Ehrhardt M, Thielemans K, Pizarro L, Atkinson D, Ourselin S, Hutton B, Arridge S
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Publication date:01/01/2015
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Journal:Inverse Problems
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Volume:31
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Article number:015001
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Status:Published
Abstract
Recent advances in technology have enabled the combination of positron
emission tomography (PET) with magnetic resonance imaging (MRI). These
PET-MRI scanners simultaneously acquire functional PET and anatomical or
functional MRI data. As function and anatomy are not independent of one
another the images to be reconstructed are likely to have shared
structures. We aim to exploit this inherent structural similarity by
reconstructing from both modalities in a joint reconstruction framework.
The structural similarity between two modalities can be modelled in two
different ways: edges are more likely to be at similar positions and/or to
have similar orientations. We analyse the diffusion process generated by
minimizing priors that encapsulate these different models. It turns out that
the class of parallel level set priors always corresponds to anisotropic
diffusion which is sometimes forward and sometimes backward diffusion.
We perform numerical experiments where we jointly reconstruct from
blurred Radon data with Poisson noise (PET) and under-sampled Fourier
data with Gaussian noise (MRI). Our results show that both modalities
benefit from each other in areas of shared edge information. The joint
reconstructions have less artefacts and sharper edges compared to
separate reconstructions and the l2-error can be reduced in all of the
considered cases of under-sampling.
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