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Dr Marcus Fruttiger
11-43 Bath Street
Tel: 0044 20 7608 6872
Fax: 0044 20 7608 6810
  • Reader of Experimental Ophthalmology
  • Inst Ophthalmology - Cell Biology
  • Institute of Ophthalmology
  • Faculty of Brain Sciences
Research Summary
Abnormal blood vessel growth in the retina is a pathological feature in numerous blinding diseases. It is therefore important to understand the cellular and molecular mechanisms that control vascular growth in the retina. We combine human tissue analysis and murine model systems based on reverse genetics and transgenic approaches to study the role of specific genes in development and disease of the retinal vasculature. We are particularly interested in interactions between blood vessels and the non-vascular components of the retina such as glial cells, neurons and the retinal pigment epithelium which are known to play important roles in controlling vessel behaviour in the retina. Knowledge gained from such basic research will be an important foundation for the development of future therapeutic approaches aiming to cure vascular pathologies in the human retina.
Academic Background
1994 PhD Doctor of Philosophy – Neurobiology Eidgenössische Technische Hochschule Zürich
1990 Dip. Diploma – Biology Eidgenössische Technische Hochschule Zürich
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