Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
- Reader in Genomics
- ICH Genetics & Genomic Medicine Prog
- Institute of Child Health
- Faculty of Pop Health Sciences
During my career, I have tried to blend technological progress with biological discovery, developing a skill set highly applicable in interdisciplinary collaborations. As a post-doc at Yale, in the laboratory of Dr David Schatz (Section of Immunobiology, Head, Dr Richard Flavell), I developed the highly cited cDNA RDA technique for the detection of differentially expressed genes1,2. Returning to the UK in 1997 I continued the theme of transcriptional regulation as a Research Fellow at the University of Sussex, focussing on the response to DNA damage. In a number of papers I helped delineate and clarify several aspects of the p53 signalling pathway3. In 1999 I took up a lectureship at UCL Institute of Child Health, continuing to publish on the DNA damage response and also developing an interest in highly parallel transcriptional assays. I established the ICH Gene Microarray Centre in 2000, which subsequently developed into UCL Genomics (www.genomics.ucl.ac.uk).
My research focuses on two areas, the global analysis of transcriptional responses and the development and application of genomic methods to biological and clinical questions.
Academic Supervision at UCL
Primary Supervisor for five PhD students at UCL: P. Evans (MRC; PhD 2005); D. Brewer, (MRC; PhD 2006), Fredrik Bryntesson: (Human Frontiers; PhD 2002), Ramya Ramanujachar (Children with Leukemia; PhD 2009), Ruth Lyons (Olivia Hodson; PhD 2009).
Secondary Supervisor for 6 PhD students: J. Yeung (PhD 2005), P. Balaraman (2005); E. Balman, Jenner Institute, (2005); M. Woodward (2007); Ching In Lau (current); Lisa Carter (current).
Teaching Activity at UCL
Course Organiser and Lecturer in Applied Genomics; MSc Module (2011 – present)
Lecturer in Genomics on MRes Biomedicine course (2002 – present).
Lecturer in Genomics on BSc Genetics course (2008 – 2012).
Lecturer in Genomic Technologies on MSc Biomechanical
Engineering course (2007 – 2008)
Lecturer in Transcriptional Analysis on UCL/Birkbeck Gene Microarray Summer School (2002 – 2012).
Lecturer in Transcriptional Analysis on MSc Gene Ontology Module (2010 – present).
|1989||PhD||Doctor of Philosophy – Endocrinology||University College London|
|1985||BA Hons||Bachelor of Arts (Honours) – Natural Sciences||University of Cambridge|