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Dr Sylvia Nagl
Darwin Building
  • Senior Lecturer
  • Structural & Molecular Biology
  • Div of Biosciences
  • Faculty of Life Sciences
I hold a BSc. Hons (First Class) and a PhD in Molecular Cell Biology, and have been a member of UCL since 1999. Prior to taking up my appointment at UCL, I was an International Post-Doctoral Fellow holding an independent fellowship in computational biology at the BioMolecular Engineering Research Center in Boston (USA) which was jointly founded by Harvard Medical School, Dana Faber Cancer Center and Boston University.
Research Summary
My research interests include systems biology, computational biology and complexity science. My current research is directed at novel applications of these inter-related research areas to the health challenges arising from global climate change.

In 2010, I published a ground-breaking text of original research with my former PhD student, with Springer Verlag: Patel M and Nagl S, The Role of Model Integration in Complex Systems Modelling.

In this text we present a solution to one of the grand challenges of systems biology, i.e. the integration of independently created mathematical models across spatio-temporal scales.

We chose to publish this in book format rather than divided into several research papers, since the presentation of the problem and its solution required an extensive and integrated explanatory treatment in longer format.

Teaching Summary
In my lectures I am addressing how computational systems biology and a complex systems methodology can be applied to enhance understanding of major diseases such as cancer, heart disease, or lung diseases. Here I am emphasising the continuum of the environmental conditions, such as urban air pollution, and the body and am seeking to generate student interest in these causative links that will become increasingly important for the health challenges of the 21st century.

Academic Background
1996 PhD Doctor of Philosophy – Molecular and Cellular Biology University of Canterbury
1990 BSc Hons Bachelor of Science (Honours) – Molecular Biology University of Canterbury
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