Help Desk: http://www.ucl.ac.uk/ras/portico/helpdesk
- Senior Research Associate
- ICH Infect, Imm, Infla. & Physio Med
- Institute of Child Health
- Faculty of Pop Health Sciences
Lentiviral vectors based on HIV make excellent vehicles to deliver genes to both dividing and non-dividing cells. This makes them useful tools for treating both inherited and acquired diseases, as well as investigating basic biology through gene expression or knockdown.
We are using this technology to study gene transfer and expression in haematopoietic stem cells to try and improve their survival in culture and to enhance stem cell transplantation treatments. Viral vectors are also being used to deliver genes for gene therapy of childhood metabolic disorders, such as Gaucher and Fabry diseases. We are also continually trying to improve the properties of the viral vectors that we use, to improve their stability, simplify their application, reduce their toxicity and enhance their efficacy.
More details of who we are, and about the work that we do, can be found in the links on this page. For further information, please get in touch; we are always pleased to discuss our work.
|2002||DIC||Diploma of the Imperial College – Molecular Biology and Genetics||Imperial College of Science, Technology and Medicine|
|2002||PhD||Doctor of Philosophy – Molecular Biology||Imperial College of Science, Technology and Medicine|
|1997||BSc Hons||Bachelor of Science (Honours) – Biology||University of Bristol|