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Prof Ali Zumla
Second Floor Clinical Microbiology, Dividion of Infection and Immunity
University College London
Royal Free Hospital Campus,Rowland Hill Street
London
NW3 2PF
Appointment
  • Professor of Infectious Diseases and International Health
  • Div of Infection & Immunity
  • Faculty of Medical Sciences
Biography

Professor Sir Alimuddin(Ali) Zumla is dually qualified in medicine(MBChB) and science(PhD). He is accredited in internal medicine and infectious diseases and is a Fellow of: 1.Royal Colleges of Physicians of London & Edinburgh; 2.Royal College of Pathologists; 3.Royal Society of Biology & 4.African Academy of Sciences. He was born in Fort Jameson, Zambia(British Northern Rhodesia). As a BEIT Scholar he completed an MSc in Clinical Tropical Medicine (Distinction & Mugratroyd prize) and PhD (Alan Woodruff Medal) from the London School of Tropical Medicine and Hygiene. He received international acclaim for rapidly identifying & notifying the 1988 Legionnaires’ disease outbreak at Portland Place, London whilst working as an infectious diseases registrar at Rush Green Hospital. After 4 years as senior registrar at the Hammersmith Hospital, Royal Postgraduate Medical School, London, he spent 3 years as Associate Professor at the University of Texas Health Science Centre at Houston,USA, & Visiting Professor at UTH in Lusaka, Zambia, before joining UCL in 1994.

Since 1994, Professor Sir Alimuddin Zumla has pioneered and championed the discipline of ‘Global Health’ at UCL. He has effectively networked numerous institutions across the world achieving significant ‘unity of purpose’ for poverty related diseases. He is a lead global advocate for developing fair and equitable North-South partnerships where close alignment of capacity development to research is central to his ethos. To take this forward he established the  UNZA-UCLMS R&D Program in 1994 (http://www.unza-uclms.org/)-a unique, novel model of 'equitable' academic partnership which has received several international awards including The European & Developing Countries Clinical Trials Partnership (EDCTP) ‘Most outstanding ‘Africa-Europe’ Team Award and Trophy' (2016).

RECENT ACCOLADES/AWARDS: Knight Bachelor of the Most Excellent Order(KBE-2017); Spinoza Award (Univ.Amsterdam-2011); Order of The Grand Commander of Distinguished Services from President of Zambia (2012); STOP-TB Partnership Kochon Prize&Medal(2012); Donald Mackay Medal from The Royal Soc Trop Med & Hygiene(2014); The Times Higher Education Award (2014); UCLHospitals-NHS-Fdn Trust Excellence Award for World Class Research (2015). In May,2016, the Karolinska Institutet, Sweden, awarded their highest distinction '(Doctorate honoris causa)' to Sir Zumla for "exceptional contributions to science, healthcare and humanity at large". In March 2017 he received the UK-National Institute for Health Research Senior Investigator Award.

PUBLICATIONS: 500 peer-reviewed PUBMED articles (ResearchGate score=51.7; GoogleScholar  H-index=81; i10index=321;and 32,160 citations). He has edited 19 medical textbooks, including the classics:Manson’s Tropical Diseases (co-ed.GC Cook),Tuberculosis:A Comprehensive Clinical Reference(co-ed.S.Schaaf), Granulomatous Disorders(co-ed.D.G.James) and Perspectives in Medicine-TB(Co-eds: S.Kaufmann & E.Rubin). He initiated & guest edited numerous journal themes series (http://www.unza-uclms.org/tb-theme-series).

Research Summary

Professor Sir Alimuddin Zumla’s research has focused on killer infectious diseases affecting adults and children:(http://www.unza-uclms.org/)

a).RESPIRATORY TRACT INFECTIONS particularly, Tuberculosis (TB), TB-HIV/AIDS co-infections., Community and Hospital acquired pneumonia.

b).INFECTIOUS DISEASES with epidemic potential which threaten global health security: i).Multi-drug resistant Tuberculosis. ii).Emerging/Re-emerging infections. iii). Antibiotic resistant infections(See website:http://www.unza-uclms.org/pandora-id-net)

1.CLINICAL TRIALS FOR EVALUATION NEW DIAGNOSTICS, DRUGS, TREATMENT AND PROPHYLACTICS FOR RESPIRATORY TRACT INFECTIONS: Professor Zumla has created and leads significant international, multi-country collaborative networks between academics, health care workers, healthcare providers, and policy makers for the conduct of multi-centre GLP/GCP clinical trials, the results of which have changed global clinical practice. Current networks span 67 partners in 34 countries across 4 continents.

2. PATHOGENESIS AND EPIDEMIOLOGICAL STUDIES: Several large autopsy study of African children and adults undertaken by Sir Zumla and teams yielded high impact data on pathogenesis of killer respiratory tract infections. Sentinel epidemiological and clinical studies showed the emergence of extensively drug resistant TB in Eastern Europe and Southern Africa. A Host-Directed Therapies network has been established to improve treatment outcomes of MDR-TB (Website:http://www.unza-uclms.org/hdt-net). Several basic science, translational clinical and operational studies are ongoing. 

3.RESEARCH INTO THE EPIDEMIOLOGY, DIAGNOSIS, TREATMENT AND PREVENTION OF KILLER RESPIRATORY INFECTIONS: Laboratory and translational clinical research on longitudinal cohorts of patients is leading to development and evaluation of rapid diagnostics (urine, sputum and blood based) and biomarkers for diagnosis, response to treatment, cure and relapse. Novel biomarkers of cytokine ratios, urine and filter paper based TB diagnostics tests have been developed. Evaluation of new and novel rapid TB diagnostic technologies in inpatient settings in paediatric and adult wards. Autopsy studies show a huge clinical load of undiagnosed sub-clinical TB now call for more pro-active screening for TB at all points of care.


Teaching Summary

1. CHAMPIONING GLOBAL HEALTH TEACHING AND CURRICULUM DEVELOPMENT: Pioneered and championed 'Global Health' at UCL since 1994 as Director of the UCL Centre for Infectious Diseases and International Health. In 1998 teamed up with Prof John Yudkin (Whittington UCL campus) to form the UCL International Health and Medical Education Centre (IHMEC). Introduced Special Study modules (SSMs) and the intercalated BSC in Global Health, and the Annual ‘Lancet’ Global Health Lectures. In 2006, when the Institute of Child Health was incorporated by UCL, it merged with IHMEC to form UCL Institute of Global Health. Subsequent Directors of UCL IGH (Prof A,Costello 2006-2014; Prof I.Abubakar 2014-date).    

2.  UNDERGRADUATE, DOCTORAL AND POSTDOCTORAL SUPERVISION AT UCL AND AS VISITING PROFESSOR TO THE SEVERAL INSTITUTIONS eg: Institute of Child Health, London; University of Zambia School of Medicine;Lusaka, Zambia; University of Amsterdam; Karolinska Institutet (Sweden), University of Tor Vergata (Rome), King AbdulAziz Univ (Jeddah). Committee Member and Secretary of the Fellowship of Postgraduate Medicine (2000-2007). Co-PI on three Europe-Africa capacity development, training and research consortia: 1. CANTAM network, 2. EACCR, 3. TESA.

3. EXTERNAL EXAMINER for MSc, MMed, MD and PhDs at several national & international universities.     

4. BOOKS: Editor of 19 textbooks including the global classic: a) Granulomatous Disorders; b) Return of the White Plague; c) Manson's Tropical Diseases, 21st and 22nd editions. d) Tuberculosis- a comprehensive Clinical Reference; e) Perspectives in Medicine-TUBERCULOSIS. Several editions of MRCP Part 1 and part 2 exam revision books. 

5. TEACHING THROUGH HIGH PROFILE JOURNAL THEME SERIES: 1). Lead 'guru' Lancet TB Theme series (2006,2010, 2012), 2). Chief Guest Editor Journal of Infectious diseases volume on TB, TB/HIV/AIDS-unanswered questions(2013), 3). Guest editor, Lancet Infectious Diseases series on Tuberculosis (2014, 2016), 4). Guest Editor Lancet Resp Med Series (2014), 5). Lancet Mass Gatherings Medicine Series (2014), 6). Lancet ID Series on Emerging RTIs (2014, 2016), 7) IJID TB series (2015 & 2017), 8) Editor, annual Current Opinion in Pulmonary Medicine Infection Series (2000-2017).9) Editor, ID Clinics of North America (2008,2012,2013). Full list on website: (http://www.unza-uclms.org/tb-theme-series).

Academic Background
2016 MD Doctor of Medicine – Medicine Karolinska Institute
2009 FRCPath Fellow of the Royal College of Pathologists – Pathology Royal College of Pathologists, UK
1994 FRCP Fellow of the Royal College of Physicians – Medicine Royal College of Physicians
1987 PhD Doctor of Philosophy – Tropical Medicine London School of Hygiene and Tropical Medicine
1984 MRCP Member of the Royal College of Physicians – Clinical Medicine Royal College of Physicians
1981 MSc Master of Science – Tropical Medicine London School of Hygiene and Tropical Medicine
1979 MB BChir Bachelor of Medicine/ Bachelor of Surgery – Medicine University of Zambia
1976 BSc Bachelor of Science – Human Biology University of Zambia
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