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Dr Jonathan Schott
Dementia Research Centre
Institute of Neurology
8-11 Queen Square
Tel: 020 3448 3553
  • Reader in Clinical Neurology
  • Neurodegenerative Diseases
  • Institute of Neurology
  • Faculty of Brain Sciences

As an undergraduate I was awarded a Wellcome Summer Studentship (1992) and a Smith-Kline-Beecham BSc Scholarship (1992). After being awarded a First Class BSc in Basic Medical Sciences with Physiology (Imperial College, 1993), I was the first undergraduate to be awarded the Edgar Lawley Travel Scholarship (1993), allowing me to continue my research at the University of Pennsylvania (USA). I gained Honours (in surgery) at medical finals, and was awarded the Malcolm Morris Memorial Prize (1996).  I joined at the Dementia Research Centre (DRC), Institute of Neurology (2001-5), where I was awarded my MD (UCL, 2004), for investigation of the role of serial magnetic resonance imaging as a tool for tracking the progressions of Alzheimer’s disease (AD) and in aiding diagnosis. The results of this work are finding application in clinical trials in AD. I have undertaken research in a range of other neurodegenerative conditions, using imaging, neurophysiology, genetics and pathology, and have contributed to the literature in many diseases. I have worked with colleagues at Oxford University on immune-mediated cognitive disorders, and was amongst the first to publish on voltage-gated potassium channel associated limbic encephalitis. After completing my clinical training, I rejoined the DRC as HEFCE/NHS Senior Lecturer/Honorary Consultant at the Institute of Neurology, UCL (2009 - ).

I was awarded an Alzheimer’s Society Training Fellowship Grant in 2002, and currently have grant support from the Alzheimer's Society, Alzheimer's Research UK, the EPSRC, EU, MRC, Wellcome Trust, NIHR UCL/H Biomedical Research Centre and Queen Square Dementia BRU, and industry collaborations (with Eli Lilly), totalling >£5M. I was awarded the Charles Symond’s Association of British Neurologists (ABN) Platform Presentation Prize (2005), and US Alzheimer's Society de Leon Prize in Neuroimaging (2011). I am a Member of the Royal College of Physicians, the British Neuropsychiatric Association, and American Academy of Neurology.

Research Groups
Research Themes
Research Summary

My research interests are centred on translational research in the dementias, including: the development and application of imaging and cerebrospinal fluid biomarkers in the degenerative dementias for early, specific diagnosis and disease tracking; atypical and young onset dementia; genotype/phenotype correlations in neurodegeneration; clinical trials; autoimmune dementia syndromes; and normal and abnormal ageing. I have several national and international collaborations, including heading an international consortium to determine the genetics of posterior cortical atrophy. I currently supervise 5 PhD students. I have published >145 Medline referenced papers in journals including the Lancet, Lancet Neurology, Annals of Neurology, Archives of Neurology, Brain, and Neurology, and have reviewed papers and grants for numerous journals and grant giving bodies, including the MRC and US NIH. I have authored editorials for journals including Neurology and the BMJ. I co-edit (with Prof Masud Husain) the Oxford Textbook of Cognition and Dementia, and authored the chapter on Alzheimer's disease and other dementias for the Oxford Textbook of Medicine. I have spoken at numerous national and international conferences, including meetings of the US Alzheimer's Association, European Federation of Neurosciences, Association of British Neurologists and American Academy of Neurology. I am an invited member of the European Federation on Neurological Sciences Dementia Panel, where the focus is on producing evidenced based practice guidelines.

Teaching Summary

 I am involved in teaching at local (undergraduate, MSc, postgraduate), national (including BMJ Neurology Masterclass, ABN) and international (European Federation of Neurological Sciences; Executive Panel of ISTAART - the International Society to Advance Research and Trteament in Alzheimer's disease). I am a member of the Royal College of Physicians Neurology Speciality Certificate Examination Standard Setting committee.

APR-2009 HEFCE Clinical Senior Lecturer Neurodegenerative Disease Institute of Neurology, UCL, United Kingdom
Academic Background
2004 MD Doctor of Medicine – Neurology University College London
1993 BSc Hons Bachelor of Science (Honours) – Medicine Imperial College of Science, Technology and Medicine
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